Research Science

The SIRT1-NAD+ Axis: A Key Target in Peptide Longevity Research

11 min read · 1900 words

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Frequently Asked Questions

What is the SIRT1-NAD+ axis?

SIRT1 is an NAD+-dependent deacetylase that regulates genes involved in metabolism, stress resistance, and longevity. As NAD+ declines with age, SIRT1 activity drops, contributing to aging. Restoring NAD+ reactivates this protective pathway.

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