IGF-1 LR3 0.1mg research peptide vial
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IGF-1 LR3 0.1mg

Insulin-like Growth Factor 1 Long R3

Purity 98%+
Form Lyophilized Powder
Molecular Weight 9111.4 g/mol
CAS Number See COA
Dosage: 0.1mg
Also known as: IGF-1 LR3, Long R3 IGF-1
Sequence: Modified 83-amino-acid IGF-1 with N-terminal extension and Arg3 substitution
Research Areas
Cell Growth Muscle Biology Cell Culture IGF Signaling
Buy at Research Vials

Overview

IGF-1 LR3 0.1mg contains the same IGF-1 LR3 analogue as the 1mg product — a modified insulin-like growth factor 1 with dramatically reduced IGFBP binding and enhanced bioavailability. It activates the IGF-1 receptor to promote cell survival, proliferation, and growth through PI3K/Akt and Ras/MAPK signaling pathways. The 0.1mg vial is suited for smaller-scale research protocols, initial dose-finding studies, or individual cell culture experiments where less total material is needed. See the IGF-1 LR3 1mg entry for comprehensive research details.

Mechanism of Action

IGF-1 LR3 0.1mg contains the same IGF-1 LR3 analogue as the 1mg product — a modified insulin-like growth factor 1 with dramatically reduced IGFBP binding and enhanced bioavailability. It activates the IGF-1 receptor to promote cell survival, proliferation, and growth through PI3K/Akt and Ras/MAPK signaling pathways. The 0.1mg vial is suited for smaller-scale research protocols, initial dose-finding studies, or individual cell culture experiments where less total material is needed. See the IGF-1 LR3 1mg entry for comprehensive research details.

Key Research Findings

  • Francis et al. (1992) demonstrated IGF-1 LR3 has reduced IGFBP binding and enhanced potency compared to native IGF-1.
  • Tomas et al. (1993) showed IGF-1 LR3 is approximately 3-fold more potent than native IGF-1 in promoting growth.
  • Clemmons (2007) reviewed the IGF/IGFBP system and IGFBP-resistant IGF analogues.

Citations & References

1

Novel recombinant fusion protein analogues of insulin-like growth factor (IGF)-I

Francis GL, Ross M, Ballard FJ, et al. — J Mol Endocrinol (1992)

2

Modifying IGF1 activity: an approach to treat endocrine disorders, atherosclerosis and cancer

Clemmons DR. — Nat Rev Drug Discov (2007)

Dosage in Research

Cell culture: 50-100 ng/mL. The 0.1mg vial is appropriate for limited cell culture experiments or pilot studies.

Dosage information is derived from published research literature and is presented for educational purposes only. This is not medical advice. All products are for laboratory research use only.

Storage & Handling

Store lyophilized (freeze-dried) powder at -20°C to 4°C in a dry environment protected from light. Unreconstituted peptide is stable for extended periods when stored properly.

Once reconstituted with bacteriostatic water or an appropriate solvent, store at 2-8°C and use within the timeframe specified on the Certificate of Analysis. Avoid repeated freeze-thaw cycles.

A Certificate of Analysis documenting purity, identity, and recommended storage conditions is included with every order.

Frequently Asked Questions

What is IGF-1 LR3 0.1mg?
A lower-concentration formulation of Long Arg3 IGF-1 for research protocols requiring precise, small-scale dosing of this modified insulin-like growth factor.
What purity is your IGF-1 LR3 0.1mg?
Our IGF-1 LR3 0.1mg is manufactured at 98%+ purity, verified through third-party HPLC analysis and mass spectrometry. A Certificate of Analysis (COA) is included with every order.
How should I store IGF-1 LR3 0.1mg?
Store lyophilized powder in a cool, dry place at 2-8°C away from direct light. Once reconstituted, refrigerate and use within the timeframe specified on the COA.
Is IGF-1 LR3 0.1mg for human use?
No. IGF-1 LR3 0.1mg is sold strictly for laboratory research use only. It is not intended for human consumption, veterinary use, or as a food additive. Products have not been evaluated by the FDA. Purchasers must be 21+ and confirm research use intent.
Where can I buy IGF-1 LR3 0.1mg?
IGF-1 LR3 0.1mg is available for purchase at researchvials.com. All orders include a COA and ship with temperature-controlled packaging.

Research Use Only

All products are intended for laboratory research and educational purposes only. Products have not been evaluated by the FDA and are not intended for human consumption, diagnosis, treatment, or prevention of any disease. Purchasers must be 21+ and confirm research use intent.